Correlation between total magnetic resonance imaging burden and carotid intima-media thickness in patients with cerebral small vessel disease
10.19845/j.cnki.zfysjjbzz.2023.0127
- VernacularTitle:脑小血管病患者磁共振成像总体负荷与颈动脉内中膜厚度的相关性研究
- Author:
Yaqin GUO
1
;
Wei SUN
1
Author Information
1. Department of Neurology,Peking University First Hospital,Beijing 100034,China
- Publication Type:Journal Article
- Keywords:
Cerebral small vessel diseases;
Ultrasonography;
Magnetic resonance imaging
- From:
Journal of Apoplexy and Nervous Diseases
2023;40(6):540-543
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the correlation between total magnetic resonance imaging(MRI) burden and carotid intima-media thickness(cIMT) in patients with cerebral small vessel disease(CSVD). Methods Clinical data,cIMT,and brain MRI data were collected from 116 CSVD patients who were hospitalized or treated at the outpatient service of Peking University First Hospital from February 2018 to August 2022,and according to total MRI burden, they were divided into low burden group(0-2 points) and high burden group(2-4 points). Univariate and multivariate logistic regression analyses were used to investigate the correlation between total MRI burden and cIMT in patients with CSVD. A receiver operating characteristic (ROC) curve was plotted to evaluate the value of cIMT in predicting high MRI burden in patients with CSVD. Results Age,hypertension,diastolic pressure,and cIMT were independently correlated with total MRI burden in patients with CSVD(P<0.05). The Spearman rank correlation analysis showed that cIMT was positively correlated with total MRI burden in patients with CSVD(r=0.319,P<0.001) and had an area under the ROC curve of 0.683(P<0.001),with a sensitivity of 0.368 and a specificity of 0.915 at the optimal cut-off value of 1.175. Conclusion This study shows that cIMT is positively correlated with total MRI burden in patients with CSVD and has a certain value in predicting total MRI burden in CSVD patients.
- Full text:2024061616015075890Correlation between total magnetic resonance imaging burden and carotid intima-media thickness in patients with cerebral small vessel disease.pdf
