Advantages of COVID-19 vaccine in the T cell immune response
10.19428/j.cnki.sjpm.2024.23382
- VernacularTitle:新型冠状病毒疫苗激发T淋巴细胞免疫作用的优势探讨
- Author:
Jiatong ZHUO
1
Author Information
1. Guangxi Zhuang Autonomous Region Center for Disease Control and Prevention， Nanning， Guangxi 530028， China
- Publication Type:News
- Keywords:
SARS-CoV-2;
mRNA vaccine;
inactivated vaccine;
T cell and B cell immune response
- From:
Shanghai Journal of Preventive Medicine
2024;36(4):409-414
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo illustrate the mechanism of COVID-19 vaccine in the T cell immune response. MethodsBased on the characteristics of T cell and B cell immune response， we matched the data of incubation periods across the SARS-CoV-2 prototype strain， Delta variants， and Omicron variants and effectiveness of mRNA and inactivated COVID-19 vaccines for analysis. ResultsThe effectiveness of mRNA COVID-19 vaccine against infection and onset was consistent with incubation period principally being ≥5 days. In contrast， the effectiveness of inactivated COVID-19 vaccine was consistent with incubation period principally being ≥8 days. ConclusionIt may be interpreted by faster T cell immune response stimulated by mRNA vaccine， compared to B cell immune response byinactivated vaccine.
