Efficacy of minocycline hydrochloride combined with cream containing prickle oil and purslane extract in treatment of rosacea
10.3760/cma.j.issn.1671-0290.2023.06.012
- VernacularTitle:米诺环素辅以含青刺果油和酸浆提取物等屏障特护霜治疗玫瑰痤疮的效果
- Author:
Yujie ZHU
1
;
Shengdong WANG
;
Xiejing FEI
;
Hong LENG
Author Information
1. 上海交通大学医学院附属第九人民医院皮肤科，上海 200011
- Keywords:
Rosacea;
Minocycline;
Inflammation;
Adjuvant therapy;
Treatment outcome
- From:
Chinese Journal of Medical Aesthetics and Cosmetology
2023;29(6):478-481
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the efficacy of minocycline combined with barrier cream containing prickly thorn fruit oil and acid slurry extract in the treatment of patients with erythematous telangiectasia or papular pustular rosacea.Methods:From August 2020 to April 2021, 44 patients with rosacea were admitted to the Department of Dermatology, the Ninth People′s Hospital, including 28 males and 16 females, aged 20-56 (37±7) years. They were randomly divided into the observation group (minocycline plus barrier cream) and the control group (minocycline plus vaseline ointment), with 22 patients in each group.Results:After 8 weeks of medication, 21 cases (95.5%) in the observation group were effective, while 16 cases (72.7%) in the control group were effective. The efficacy of the observation group was better than that of the control group, the difference was statistically significant (χ 2=2.06, P=0.039). No significant adverse reactions were observed in both groups. Conclusions:Minocycline combined with barrier cream containing prickly thorn oil and acid slurry extract has a good therapeutic effect on rosacea, which is worthy popularizing.
