Advances in the research of lateral flow assays applied in detecting disease biomarkers
10.3760/cma.j.cn114452-20231101-00249
- VernacularTitle:侧流层析技术在疾病生物标志物检测中的应用研究进展
- Author:
Hao XIE
1
;
Xinyu SONG
;
Enjie SUN
;
Junhui GUO
Author Information
1. 武汉理工大学化学化工与生命科学学院,武汉 430070
- Keywords:
Chromatography;
Biomarkers;
Clinical laboratory techniques
- From:
Chinese Journal of Laboratory Medicine
2024;47(2):192-196
- CountryChina
- Language:Chinese
-
Abstract:
Biomarkers is of great significance for clinical diagnosis. Lateral flow assay (LFA) is a test method which developed based on paper chromatography and has a wide range of applications in testing disease biomarkers. The current researches of LFA mainly focus on the detection specificity, precision and sensitivity, as well as multiple detection of disease markers or simultaneous detection of multiple diseases. This artical reviews the systemic design, working principles of LFA along with the application research of LFA in detecting disease markers, in order to provide reference for development and application of LFA.