Capillary electrophoresis-mass spectrometry and its application in laboratory medicine
10.3760/cma.j.cn114452-20231114-00280
- VernacularTitle:毛细管电泳-质谱联用技术及其在检验医学中的应用
- Author:
Zuojun SHEN
1
Author Information
1. 中国科学技术大学附属第一医院检验科，合肥 230001
- Keywords:
Electrophoresis, capillary;
Mass spectrometry;
Molecular structure;
Interface
- From:
Chinese Journal of Laboratory Medicine
2024;47(1):14-19
- CountryChina
- Language:Chinese
-
Abstract:
Capillary electrophoresis has high sensitivity and high separation efficiency, and mass spectrometry can provide structural information of samples. The combination of capillary electrophoresis and mass spectrometry can form powerful capabilities on qualitative and quantitative analysis. The presence of capillary electrophoresis-mass spectrometry makes it possible to accurately analyze the structure and molecular weight of bioactive components at the nanoscale sample level, or even at the single-cell level, which is an indispensable technology platform for the analysis of biological samples. With the development of this technique, the applications of capillary electrophoresis-mass spectrometry began to emerge in the field of clinical testing.
