Pathogenesis and prevention of exercise-related kidney injury
10.3760/cma.j.cn441217-20221214-01222
- VernacularTitle:运动相关肾损伤的发病机制及防治措施
- Author:
Xieguanxuan XU
1
;
Guangyan CAI
Author Information
1. 解放军医学院，解放军总医院第一医学中心肾脏病医学部，肾脏疾病全国重点实验室，国家慢性肾病临床医学研究中心，北京 100853
- Keywords:
Acute kidney injury;
Exercise;
Kidney diseases;
Mechanism;
Prevention
- From:
Chinese Journal of Nephrology
2023;39(10):786-792
- CountryChina
- Language:Chinese
-
Abstract:
The risk factors of acute kidney injury caused by strenuous exercise include dehydration of the body, elevated body temperature, and intake of large amounts of sugary drinks after exercise, etc. The possible mechanism of the injury may be the inflammatory reaction of the body or the kidney itself, and the accumulation of various metabolites causing damage to the structure and function of the kidney under the induction of various risk factors. Repeated exposure to those risk factors not only increase the risk of acute kidney disease, but also may lead to chronic kidney disease. The paper reviews the definition, epidemiology, clinical manifestations, pathogenesis, and prevention measures of exercise-related kidney injury, to provide guidance for the formulation of appropriate exercise programs.
