International frontier hot spots and recent advances of donor specific antibody and antibody - mediated rejection after kidney transplantation

VernacularTitle:肾移植供者特异性抗体和抗体介导排斥反应的国际前沿热点、进展及其临床思考
Author: Xianghui WANG ¹ ; Huimin AN
Author Information

1. 上海交通大学医学院附属瑞金医院泌尿外科肾脏移植中心，上海　200025
Keywords: Kidney transplantation; Donor specific antibody; Antibody-mediated rejection; Recent advance
From: Chinese Journal of Organ Transplantation 2024;45(1):18-25
CountryChina
Language:Chinese
Abstract: This review summarized the international hot topics and recent advances of donor specific antibody (DSA) and antibody-mediated rejection (AMR) after kidney transplantation, including a novel understanding of DSA, risk stratification, non-HLA antibody impairments, new application strategies of desensitization and AMR treatment, as well as striking a balance between AMR management and infection risk. Also institutional reflections and evaluations were discussed based upon clinical practices.