Clinical application of targeted drugs in vitiligo: progress and prospects
- VernacularTitle:白癜风靶向药物临床应用进展及前景
- Author:
Shuli LI
1
;
Chunying LI
Author Information
- Keywords: Vitiligo; Janus kinases; Enzyme inhibitors; Tofacitinib; Simvastatin; Alpha-melanocyte stimulating hormone
- From: Chinese Journal of Dermatology 2024;57(1):12-16
- CountryChina
- Language:Chinese
- Abstract: In recent years, great progress has been made in the research on the pathogenesis of vitiligo, and many new treatment methods and drugs have emerged. Interferon-γ-activated Janus kinase (JAK) signaling and melanocyte regeneration signaling pathways are the most concerned targets in the research on the treatment of vitiligo. This article summarizes the efficacy of current new drugs targeting these pathways and the experience in applying these drugs in the treatment of vitiligo. JAK inhibitors are currently the most promising new drugs for the treatment of vitiligo, and their efficacy can be improved in combination with phototherapy.
