Mechanism of action of long non-coding RNAs in cutaneous squamous cell carcinoma
- VernacularTitle:长链非编码RNA在皮肤鳞状细胞癌中的作用机制进展
- Author:
Rong LI
1
;
Kun CHEN
;
Jiaan ZHANG
Author Information
- Keywords: Neoplasms, squamous cell; RNA, untranslated; Epigenomics; Alternative splicing; Long non-coding RNA; Pathogenesis; Cutaneous squamous cell carcinoma
- From: Chinese Journal of Dermatology 2023;56(10):985-988
- CountryChina
- Language:Chinese
- Abstract: Long non-coding RNAs (lncRNAs) participate in the occurrence and development of cutaneous squamous cell carcinoma (cSCC) mainly through epigenetic modification, mRNA alternative splicing, and binding to microRNAs. This review focuses on recent research progress in regulatory role of lncRNAs in cSCC, and discusses their mechanisms of action, aiming to seek potential therapeutic targets and biomarkers for cSCC.
