Clinical effects of Modified Sanzi Yangqin Decoction combined with acupuncture on patients with chronic obstructive pulmonary disease at stable stage complicated with sarcopenia
10.3969/j.issn.1001-1528.2024.01.018
- VernacularTitle:三子养亲汤加减联合针刺对慢性阻塞性肺疾病稳定期合并肌少症患者的临床疗效
- Author:
Yan-Li ZHANG
1
;
Yi-Xing SONG
;
Dan XU
Author Information
1. 三亚市中医院呼吸科, 海南 三亚 572000
- Keywords:
Sanzi Yangqin Decoction;
acupuncture;
conventional treatment;
chronic obstructive pulmonary disease at stable stage;
sarcopenia
- From:
Chinese Traditional Patent Medicine
2024;46(1):107-111
- CountryChina
- Language:Chinese
-
Abstract:
AIM To explore the clinical effects of Modified Sanzi Yangqin Decoction combined with acupuncture on patients with chronic obstructive pulmonary disease at stable stage complicated with sarcopenia.METHODS Ninety-four patients were randomly assigned into control group(47 cases)for 8-week intervention of conventional treatment,and observation group(47 cases)for 8-week intervention of Modified Sanzi Yangqin Decoction,acupuncture and conventional treatment.The changes in clinical effects,TCM syndrome scores,and levels of pulmonary function indices(FVC,FEV1,FEV1/FVC),inflammatory factors(CRP,IL-6,TNF-α),muscle-specific biomarkers(MSTN,IGF-1),relevant scale scores(SARC-F,SPPB)and skeletal muscle mass index were detected.RESULTS The observation group demonstrated higher total effective rate than the control group(P<0.05).After the treatment,the two groups displayed decreased TCM syndrome scores,inflammatory factors,MSTN,SARC-F score(P<0.05),and increased pulmonary function indices,IGF-1,SPPB score,skeletal muscle mass index(P<0.05),especially for the observation group(P<0.05).CONCLUSION For the patients with chronic obstructive pulmonary disease at stable stage complicated with sarcopenia,Modified Sanzi Yangqin Decoction combined with acupuncture exhibits significant clinical efficacy.
