Simultaneous content determination of eight Schisandra lignans in Hugan Tablets by UPLC
10.3969/j.issn.1001-1528.2024.01.003
- VernacularTitle:UPLC法同时测定护肝片中8种五味子木脂素的含量
- Author:
Zhi-Yuan ZHAO
1
;
Jin-Peng ZHANG
;
Shuo ZHAO
;
Yuan-Yuan LIU
Author Information
1. 山东第一医科大学 (山东省医学科学院) 药学院, 山东 泰安 271016
- Keywords:
Hugan Tablets;
Schisandra lignans;
content determination;
UPLC
- From:
Chinese Traditional Patent Medicine
2024;46(1):10-14
- CountryChina
- Language:Chinese
-
Abstract:
AIM To establish a UPLC method for the simultaneous content determination of schisandrol A,gomisin J,schisandrol B,angeloylgomisin H,angeloylgomisin Q,schisanhenol,deoxyschizandrin and schisandrin C in Waigan Fenghan Granules.METHODS The analysis was performed on a 40℃thermostatic WELCH Ultimate?-C18 column(100 mm×2.1 mm,1.8 μm),with the mobile phase comprising of acetonitrile-0.1%formic acid flowing at 0.3 mL/min in a gradient elution manner,and the detection wavelength was set at 267 nm.RESULTS Eight Schisandra lignans showed good linear relationships within their own ranges(R2≥0.998 3),whose average recoveries were 96.47%-104.96%with the RSDs of 0.62%-1.60%.CONCLUSION This simple,rapid and accurate method can be used for the quality control of Hugan Tablets.
