Predictive value of baseline serum electrolyte levels for adverse prognosis in patients with severe traumatic brain injury in Lanzhou Plateau
10.3969/j.issn.1009-0126.2023.12.024
- VernacularTitle:兰州高原地区重型创伤性脑损伤患者基线血清电解质水平对不良预后风险的预测价值
- Author:
Li CAO
1
;
Xia FENG
;
Chunxia DOU
;
Jie ZHOU
Author Information
1. 730050 兰州,解放军联勤保障部队第九四○医院神经外科
- Keywords:
brain injuries,traumatic;
electrolytes;
logistic models;
forecasting;
prognosis;
risk factors
- From:
Chinese Journal of Geriatric Heart Brain and Vessel Diseases
2023;25(12):1332-1335
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the predictive value of baseline serum electrolyte levels for adverse prognosis in patients with severe traumatic brain injury(sTBI)in Lanzhou Plateau Area.Methods A total of 210 sTBI patients admitted to our hospital were enrolled,and then divided into good progno-sis group(91 cases)and poor prognosis group(119 cases)according to clinical outcome.The clinical data and serum electrolyte levels were compared between the two groups.Multivariate logistic regres-sion analysis was used to analyze the influencing factors of poor prognosis,and ROC curve was plot-ted to analyze the predictive value of the influencing factors.Results There were significant differ-ences in diabetes,GCS score,serum calcium and magnesium levels between the two groups(P＜0.05,P＜0.01).Multivariate logistic regression analysis showed that diabetes(OR=3.483,95％CI:1.452-8.357),GCS score(OR=0.464,95％CI:0.3 6 3-0.594),hypocalcemia(OR=6.243,95％CI:3.353-11.626)and hypermagnesemia(OR=9.985,95％CI:1.251-19.701)were the influencing factors for poor prognosis of sTBI patients.ROC curve analysis showed that the AUC val-ue was 0.702(95％CI:0.635-0.763)in hypocalcemia and 0.565(95％CI:0.495-0.633)in hy-permagnesemia for the prediction.Conclusion Diabetes,low GCS score,hypocalcemia and hypermag-nesemia are risk factors for poor prognosis of sTBI patients at high altitude.Hypocalcemia has good predictive value in the prediction and can be used as an independent predictor.
