Prognosis of congenital bile duct cysts after cyst resection and risk factors analysis of postoperative biliary calculus
10.3760/cma.j.cn113884-20231102-00119
- VernacularTitle:先天性胆管扩张症患者囊肿切除术后的预后情况以及术后发生胆道结石的风险因素分析
- Author:
Yonghua ZHU
1
;
Min SUN
;
Chen WU
;
Hui ZHANG
;
Aihua YAO
Author Information
1. 南京医科大学第一附属医院肝胆中心，南京 210029
- Keywords:
Bile ducts;
Congenital bile duct cysts;
Gallstone;
Postoperative complication;
Malignancy
- From:
Chinese Journal of Hepatobiliary Surgery
2024;30(2):114-118
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the prognosis of congenital bile duct cysts following cyst resection, and to analyze the risk factors associated with the development of postoperative biliary calculus.Methods:Clinical data of 149 patients with congenital bile duct cysts undergoing surgery in the First Affiliated Hospital of Nanjing Medical University from May 2004 to January 2022 were retrospectively analyzed, including 59 males and 90 females, with a median age of 32 (21, 47) years old. Patients were divided into two groups: the stone group ( n=51, biliary calculus occurred during the follow-ups after surgery) and non-stone group ( n=98). Clinical data such as gender, age, medical history, cyst type, biliary calculus, anastomotic stenosis and occurrence of cancer were compared. All patients were followed up via telephone consultations. A logistic regression analysis was used to identify the risk factors associated with the occurrence of biliary calculus after surgery. Results:The duration of the follow-ups was 120 (24, 211) months. The observed incidence of postoperative biliary calculus, anastomotic stricture, and cancer in the patients were 34.2% (51/149), 8.7% (13/149), and 4.7% (7/149), respectively. The logistic regression analysis indicated that incomplete cyst resection ( OR=3.332, 95% CI: 1.221-9.094) and postoperative anastomotic stenosis ( OR=13.300, 95% CI: 2.586-68.401) were associated with a higher risk of biliary calculus formation after cystectomy (all P<0.05). Conclusion:Patients with congenital bile duct cysts suffer a high risk of biliary calculus formation after cystectomy. The residual cyst and postoperative anastomotic stenosis are independent risk factors for biliary calculus after surgery.
