Radiotherapy for head and neck cancer: oral complications and treatment

VernacularTitle:头颈部肿瘤放疗相关口腔并发症和治疗
Author: Zhi WANG ¹ ; Yingzi PAN ; Mingsheng CHEN ; Fengchao WANG
Author Information

1. 陆军军医大学基础医学院　重庆医科大学附属口腔医院　陆军军医大学军事预防医学系　防原医学教研室　创伤与化学中毒全国重点实验室，重庆　400038
Keywords: Head and neck cancer; Radiotherapy; Oral mucosa; Salivary glands; Dental caries
From: Chinese Journal of Radiological Medicine and Protection 2023;43(9):752-758
CountryChina
Language:Chinese
Abstract: Radiotherapy, as a common modality for the treatment of head and neck cancer (HNC), frequently induces oral and maxillofacial complications. However, the complex tissues and diverse pathogeneses of these regions lead to limited treatment protocols and research progress currently. This paper systematically summarizes radiation-induced oral mucositis, salivary gland injury, and dental caries in radiotherapy for HNC and reviews existing pathogenetic hypotheses, treatment, and research progress. The purpose is to provide some reference for further research on relevant pathological mechanisms and the development of new preventive and treatment methods.