Research Progress in TCM Regulating Exosomes in Diabetic Kidney Disease
10.19879/j.cnki.1005-5304.202303098
- VernacularTitle:中医药调节外泌体干预糖尿病肾脏疾病研究进展
- Author:
Ming ZHAO
1
;
Yanming HE
;
Zeng ZHANG
;
Zheng YAO
Author Information
1. 上海中医药大学附属岳阳中西医结合医院,上海 200083
- Keywords:
diabetic kidney disease;
exosomes;
miRNA;
TCM;
review
- From:
Chinese Journal of Information on Traditional Chinese Medicine
2024;31(4):183-186
- CountryChina
- Language:Chinese
-
Abstract:
Diabetic kidney disease(DKD)is a common microvascular complication of diabetes mellitus.Exosomes play a key role in mesangial cell proliferation,podocyte apoptosis,and epithelial mesenchymal transformation induced by renal tubular epithelial cells,which are important links in the pathogenesis of DKD.Based on the correlation of abnormal function of exosomes of DKD with theory of"disperse essence by spleen qi"and the theory of"kidney collaterals stasis"in TCM,this article reviewed the research progress and regulation mechanism of TCM in regulating exosomes to intervene in diabetic kidney disease,providing reference for related research.