Treatment of blastocytic plasmacytoid dendritic cell tumor with bone marrow involvement and no skin lesions: a case report

VernacularTitle:骨髓受累且无皮损表现的母细胞性浆细胞样树突细胞肿瘤1例治疗体会
Author: Ruiping WANG ¹ ; Yan YAN
Author Information

1. 内蒙古自治区巴彦淖尔市医院血液内科，巴彦淖尔　015000
Keywords: Blastic plasmacytoid dendritic cell neoplasm; Bone marrow; Decitabine; Venetoclax; Therapy
From: Clinical Medicine of China 2024;40(2):120-122
CountryChina
Language:Chinese
Abstract: Plasm Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) is a rare and highly invasive hematological malignancies. Typical BPDCN usually starts with skin lesions, involves lymph nodes, bone marrow, central nervous system and other soft tissues. It is not sensitive to chemotherapy and radiotherapy, and the prognosis is very poor. A patient with abdominal pain, anemia, hepatosplenomegalosis as the first manifestations, and lack of typical skin lesions was admitted in Bayannur Hospital on August 28, 2020. BPDCN was finally diagnosed by bone marrow morphology, flow cytometry and bone marrow biopsy. Provide reference for clinical doctors to indentify and treat BPDCN by analyzing the clinical data of rare BPDCN cases with no skin lesions.