Establishment and of preliminary verification of automatic auditing rules for routine coagulation assays
10.3969/j.issn.1672-8270.2024.01.027
- VernacularTitle:常规出凝血检验自动审核规则的建立与验证
- Author:
Ping DI
1
;
Feng DONG
;
Xueying YU
;
Meihua WANG
;
Wei JIANG
;
Yue LI
;
Jun CAO
;
Hong ZHANG
;
Weixin WANG
;
Mianyang LI
Author Information
1. 解放军总医院第一医学中心检验科 北京 100853
- Keywords:
Diagnostic tests;
Blood coagulation tests;
Clinical laboratory technology;
Clinical laboratory information system;
Time factors
- From:
China Medical Equipment
2024;21(1):135-140
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To establish auto verification rules for the routine coagulation assays,and to provide reference for clinical laboratories to improve the quality and efficiency of results verification.Methods:A total of 24,510 specimens of sodium citrate anticoagulation routine coagulation test from the laboratory departments of eight hospitals including the First Medical Center,Chinese PLA General Hospital during January to March 2020 were collected and randomly divided into a rule establishment group and a rule verification group,with 6,670 specimens in the rule establishment group,including 2,056 Delta checks,and 17,840 specimens in the rule validation group,including 3,210 Delta checks.The activities of prothrombin time(PT),activated partial thromboplastin time(APTT),fibrinogen(Fib),thrombin time(TT),D-dimer(DD)and/or antithrombin(AT)were detected by Stago STA R Max automatic coagulation analyzer and supporting reagents.Taking the manual verification results as the standard,the auto verification and manual false negative rate(invalid verification),false positive rate(invalid interception),pass rate,positive coincidence rate,negative coincidence rate,verification consistency rate and specimen turnaround time(TAT)of the two groups were calculated.Results:The auto verification rules and the application process were preliminarily established,including internal quality control,alarm information,auto verification scope,critical value and deviation value inspection.In the rule establishment group,the single item pass rate was 82.6%-92.4%,and the overall pass rate was 73.8%.The consistency rate between auto verification and manual verification was 98.2%,and the positive coincidence rate and negative coincidence rate were 24.4%and 73.8%,respectively.In the rule verification group,the single item pass rate was 86.4%-91.5%,and the overall review pass rate was 71.5%.By simulating the application of auto verification rules,the average TAT of two hospitals among the eight hospitals was shortened by 1.5 hours and 2.1 hours,respectively.Conclusion:The application of auto verification rules can reduce workload of manual verification,and significantly shorten the TAT,and improve the report efficiency of the laboratory.
