Prenatal ultrasonic diagnosis of congenital anomalies of kidney and urinary tract during 2012-2022
10.13929/j.issn.1003-3289.2023.12.002
- VernacularTitle:2012-2022年产前超声诊断先天性肾脏和尿路畸形
- Author:
Qianqian GAO
1
;
Hong LUO
Author Information
1. 四川大学华西第二医院超声科出生缺陷与相关妇儿疾病教育部重点实验室,四川成都 610041
- Keywords:
fetus;
urologic diseases;
ultrasonography,prenatal
- From:
Chinese Journal of Medical Imaging Technology
2023;39(12):1764-1769
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the accuracy of prenatal ultrasonic diagnosis for congenital anomalies of the kidney and urinary tract(CAKUT)as well as pregnancy outcomes before and after implementation of the two-child and three-child policy in China during 2012-2022.Methods Data of 53 857 pregnant women with 158 CAKUT fetuses in pre-policy group,and 167 627 pregnant women with 521 CAKUT fetuses in post-policy group were retrospectively analyzed.The incidence rate of fetal CAKUT,the accuracy of prenatal ultrasonic diagnosis and the birth rate of CAKUT were compared groups.Results The incidence rate of fetal CAKUT was 0.31％(521/167 627)in post-policy group and 0.29％(158/53 857)in pre-policy group,in the former was lower than in the latter(P＞0.05).Pregnant women with CAKUT fetus in post-policy group was older than in pre-policy group([29.2±4.6]years vs.[27.0±4.3]years,P＜0.05),while prenatal ultrasonic diagnosis of CAKUT in post-policy group was earlier than in pre-policy group([25.3±7.3]weeks vs.[27.8±7.1]weeks,P＜0.05).No significant difference of diagnostic accuracy of prenatal ultrasound of CAKUT,of upper urinary tract related abnormalities,lower urinary tract related abnormalities nor single CAKUT was found between groups(all P＞0.05).The proportion of extra-renal urinary system abnormalities was the highest in both groups.The accuracy of prenatal ultrasound diagnosis of other system abnormalities in post-policy group was lower than that in pre-policy group(all P＜0.05).The accuracy of prenatal ultrasonic diagnosis of posterior urethral valve formation in post-policy group was higher than that in pre-policy group(100％vs.50.00％,P＜0.05),but no significant difference of other abnormal manifestations was detected between groups(all P＞0.05).Terminate pregnancy occurred in 143 fetuses with CAKUT,while other 536 fetuses continued pregnancy.There was no significant difference of the birth rate of CAKUT fetuses with upper urinary tract related abnormalities,lower urinary tract related abnormalities nor other system abnormalities between groups(all P＞0.05).The birth rate fetuses with single CAKUT in post-policy group was higher than that in pre-policy group(97.61％vs.93.18％,P＜0.05).Conclusion With the implementation of two-child and three-child policy of China,the average prenatal ultrasonic diagnosis of CAKUT became earlier,the accuracy of prenatal ultrasonic diagnosis of CAKUT and the birth rate of fetus with single CAKUT increased.
