Autologous platelet-rich plasma treatment for infected deep second-degree burn wounds: a case report
10.13303/j.cjbt.issn.1004-549x.2024.01.017
- VernacularTitle:自体富血小板血浆治疗深二度烧伤合并感染创面的探讨
- Author:
Hao HUANG
1
;
Jun HUANG
2
;
Qun LIANG
1
;
Jian LIU
2
;
Ting LI
2
;
Yang ZHAO
1
Author Information
1. Department of Blood Transfusion, Guangzhou Red Cross Hospital, Guangzhou 510220, China
2. Department of Burn and Plastic Surgery, Guangzhou Red Cross Hospital, Guangzhou 510220, China
- Publication Type:Journal Article
- Keywords:
platelet-rich plasma (PRP);
burn;
wound repair;
wound infection
- From:
Chinese Journal of Blood Transfusion
2024;37(1):95-100
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To explore the feasibility of using autologous platelet-rich plasma (PRP) in the treatment of deep second-degree burns complicated with wound infection. 【Methods】 A retrospective analysis was conducted on the treatment process of a patient with deep second-degree burns and bacterial infection on the wound using autologous PRP. Clinical treatment highlights and outpatient follow-up were combined to discuss the feasibility and clinical effects of using autologous PRP in the treatment of burn wounds complicated with infection. 【Results】 The patient had a deep second-degree burn with a coagulase-negative Staphylococcus infection on the left lower limb. After one week of conventional wound dressing and antibiotic treatment, the patient's body temperature returned to normal. However, wound healing was slow and yellow secretion persisted. Subsequently, the burn wound was treated combined with topical autologous PRP. The wound pain score gradually decreased from 8 to 1. After 2 weeks, the bacterial culture of the wound secretion was negative, and the wound healed completely after 18 days. The wound scar score decreased from 5 to 2 at 1, 3 and 6 months after PRP treatment, and no obvious scar formation was observed. In the course of PRP treatment, there were no adverse reactions such as increased wound inflammation, abnormal blood routine and liver and kidney function test results. 【Conclusion】 For deep second-degree burn patients with localized wound bacterial infections who either refuse surgery or are not suitable for surgery, autologous PRP is a safer alternative that can effectively promote tissue regeneration and wound healing. The patient in this case achieved a curative effect in a short period of time.
