Molecular characteristics of enteropathogenic Escherichia coli isolates from livestock at a monitoring point in Jiangsu Province
10.3969/j.issn.1002-2694.2024.00.002
- VernacularTitle:江苏省某监测点家畜来源肠致病性大肠埃希菌分离株分子特征分析
- Author:
Xiao-Xiao KONG
1
;
Yue HAN
;
Lu ZHOU
;
Xiao-Qing CHENG
;
Chen DONG
Author Information
1. 国家卫生健康委员会肠道病原微生物重点实验室,江苏省疾病预防控制中心,南京 210009
- Keywords:
enteropathogenic Escherichia coli;
infectious diarrhea;
molecular characteristic analysis
- From:
Chinese Journal of Zoonoses
2024;40(1):56-61
- CountryChina
- Language:Chinese
-
Abstract:
This study was aimed at analyzing the molecular characteristics of enteropathogenic Escherichia coli(E.coli)strains isolated from domestic animals at a surveillance site in Jiangsu province and evaluating their potential pathogenicity,to provide evidence supporting the surveillance,prevention,and control of infectious diarrhea.Thirty-seven EPEC strains isolated from domestic animals at this surveillance site were characterized by whole genome sequencing.All EPEC strains isolated from local livestock were aEPEC,which has a variety of serotypes and carries a variety of virulence genes associated with diarrhea.Nine ST types with regional epidemic characteristics were identified.Five eae gene subtypes were found,among which β1 was dominant and was also the most common strain in patients with diarrhea.According to analysis of the characteristics of 37 EPEC strains,all EPEC strains from local livestock were aEPEC,thus posing a potential threat to public health.Monitoring of livestock feces and the breeding environment must be strengthened in the surveillance of infectious diarrhea.
