Research progress on the cerebral white matter hyperintensities regression

VernacularTitle:脑白质高信号消退的研究进展
Author: Yuyun XU ¹ ; Qifen FANG ; Xiangyang GONG
Author Information

1. 310014 杭州,浙江省人民医院(杭州医学院附属人民医院)放射科
Keywords: Cerebral small vessel diseases; White matter; Magnetic resonance imaging; Review
From: Chinese Journal of Cerebrovascular Diseases 2024;21(3):188-193
CountryChina
Language:Chinese
Abstract: White matter hyperintensities(WMH)is prevalent in the elderly population and is associated with stroke,cognition,gait instability,and neuropsychiatric symptoms.WMH burden usually increases with the growth of age.However,in recent years,there are researches found that WMH is actually dynamic variable.During the development,part of the WMH may regress,accompanied by the slowdown of brain atrophy and cognitive improvement.While,its mechanism,influencing factors and clinical significance remains unclear,and the effective treatment to reverse WMH is not clear.The article reviewed the current studies on the regression of WMH,aiming to provide reference for clinicians to actively perform intervention in the WMH related factors,promote their reversal in the early stage and improve the brain health of patients.