Complement lectins and respiratory diseases
10.3969/j.issn.1000-484X.2024.03.034
- VernacularTitle:补体凝集素与呼吸系统疾病
- Author:
Shixiong WANG
1
;
Hao NIE
;
Haochuan ZHANG
;
He HUANG
Author Information
1. 安徽医科大学深圳二院临床学院,深圳市第二人民医院呼吸与危重症医学科,深圳 518035
- Keywords:
Ficolin;
Mannose-binding lectin;
Complement;
Respiratory diseases
- From:
Chinese Journal of Immunology
2024;40(3):641-644,650
- CountryChina
- Language:Chinese
-
Abstract:
The complement lectin pathway is an important means to exert immune effect.Ficolin and Mannan-binding lectin(MBL)are the initiators of complement pathway.Both structure and function are very similar.They can activate the complement path-way by recognizing certain substances on the surface of pathogens,emphasizing phagocytosis or directly kill and dissolve related patho-gens,thereby playing an important role in the immune system,especially in fighting infection.The respiratory system diseases are mostly infectious diseases.In recent years,there have been reports that ficolin/MBL is related to many other respiratory diseases.This article discusses the related research of ficolin/MBL and respiratory diseases,hopes to provide theoretical support for related research.
