Motor function and quality of life in Parkinson's disease patients with freezing of gait
10.3969/j.issn.1006-9771.2024.03.012
- VernacularTitle:帕金森病伴冻结步态患者的运动功能和生活质量
- Author:
Ying GE
1
;
Wowa ZHAO
;
Lu ZHANG
;
Xuan SHU
;
Jiawei LI
;
Ying LIU
Author Information
1. 中国医学科学院北京协和医院康复医学科,北京市 100730
- Keywords:
Parkinson's disease;
freezing of gait;
motor;
quality of life
- From:
Chinese Journal of Rehabilitation Theory and Practice
2024;30(3):339-344
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the differences in motor function and quality of life among mild-to-moderate Parkinson's disease(PD)patients with or without freezing of gait(FOG),and the correlation of FOG to motor function and quality of life. Methods From April,2021 to December,2022,132 mild-to-moderate PD patients aged 60 to 80 years were selected from Peking Union Medical College Hospital,and were divided into FOG group(n = 43)and non-FOG group(n = 89)according to the clinical features.They were assessed with Freezing of Gait Questionnaire(FOGQ),Berg Balance Scale(BBS),Timed"Up&Go"Test(TUGT),Five Times Sit to Stand Test(FTSST),isokinetic muscle strength,Unified Parkinson's Disease Rating Scale(UPDRS)and 39-item Parkinson's Disease Question-aire-39(PDQ-39). Results The BBS score was lower(Z =-2.354,P<0.05),and the TUGT,FTSST,UPDRS part 2 and part 3 scores,and the Parkinson's disease summary index(PDSI)were higher in FOG group than in non-FOG group(Z>3.074,t = 2.748,P<0.01).FOGQ score correlated with BBS score,UPDRS Part 2 and Part 3 scores,and PDSI(|r|>0.392,P<0.001). Conclusion FOG would impair motor function,activities of daily living and quality of life in mild-to-moderate PD pa-tients,and increase the risk of falls.
