Current status and advances of cytomegalovirus pneumonia after hemato-poietic stem cell transplantation
10.12138/j.issn.1671-9638.20243543
- VernacularTitle:造血干细胞移植术后巨细胞病毒肺炎的现状与进展
- Author:
Yan-Hua ZHENG
1
;
Rui-Lin REN
;
Xiao-Fan LI
Author Information
1. 福建省血液病研究所,福建 福州 350000;中国医科大学附属第一医院血液科,辽宁 沈阳 110000
- Keywords:
hematopoietic stem cell transplantation;
cytomegalovirus;
pneumonia;
imaging omics;
prophylactic treatment
- From:
Chinese Journal of Infection Control
2024;23(1):126-132
- CountryChina
- Language:Chinese
-
Abstract:
Cytomegalovirus(CMV)pneumonia is one of the common complications of hematopoietic stem cell transplantation,and is also a significant cause leading to patient death.Due to the poor prognosis of CMV pneumo-nia,intervention measures are necessary to prevent CMV reactivation and progress to CMV pneumonia.At present,clinical medication mainly relies on preemptive treatment strategies,and the timing of medication depends on the timeliness of early diagnosis.However,feasible methodology and measures for the early diagnosis of CMV pneumo-nia in clinical practice are relatively limited.Meanwhile the diagnostic gold standard operation is invasive,causing trauma to a certain degree,and the detection timeliness is poor.This review summarizes the clinical status and ad-vances in the diagnosis and drug prophylactic treatment of CMV pneumonia after hematopoietic stem cell transplan-tation,and explores possible development directions and trends in the future.
