Comparative analysis of therapeutic plasma exchange with different types of blood cell separators
10.19745/j.1003-8868.2023207
- VernacularTitle:不同型号血细胞分离机行血浆置换治疗的差异比较
- Author:
Wen-Ting WANG
1
;
Yan ZHENG
;
Dong-Xia REN
;
Xiao-Qing WANG
;
Lin WANG
Author Information
1. 空军军医大学唐都医院输血科,西安 710038
- Keywords:
blood cell separator;
plasma exchange;
replacement fluids;
anticoagulant
- From:
Chinese Medical Equipment Journal
2023;44(10):55-58
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze and compare the therapeutic effects of COM.TEC and COBE Spectra blood cell separators in therapeutic plasma exchange.Methods Totally 20 patients admitted to some hospital from March to July 2022 were selected as the study subjects prospectively,and then divided into A and B groups randomly.Therapeutic plasma exchange was carried out with COM.TEC blood cell separator in group A(10 cases,42 treatments)and COBE Spectra blood cell separator in group B(10 cases,36 treatments).The two groups were compared in terms of anticoagulant dosage,plasma exchange time and adverse events.SPSS 25.0 software was used for statistical analysis.Results The anticoagulant dosage for per liter of circulating blood volume in group A was(76.83±7.80)mL,which was significantly lower than that((83.89±1.16)mL)in group B(t=5.040,P＜0.05).When the fluid balance was set to 100％,the plasma exchange time for per liter of plasma in group A was(38.39±5.74)min,which was statistically shorter than that((42.30±5.35)min)in group B(t=3.528,P＜0.05).There were 11 adverse events in group A including 2 allergic reactions and 9 instrument alarms,and 8 adverse events in group B including 4 allergic reactions and 4 instrument alarms.Conclusion Both COM.TEC and COBE Spectra blood cell separators can meet the requirements for clinical treatment in spite of differences in performances,and the blood cell separator has to be selected properly for therapeutic plasma exchange based on patient conditions.[Chinese Medical Equipment Journal,2023,44(10):55-58]
