Meta-analysis of the myopia control effect of orthokeratology lenses with dif-ferent back optical zone diameters
10.13389/j.cnki.rao.2024.0061
- VernacularTitle:不同后光学区直径角膜塑形镜控制近视效果的Meta分析
- Author:
Wenting WANG
1
;
Lu QIAO
;
Lemin CHEN
;
Shaomin PENG
Author Information
1. 230031 安徽省合肥市,安徽医科大学附属爱尔眼科医院;750000 宁夏回族自治区银川市,宁夏爱尔眼科医院
- Keywords:
orthokeratology lens;
myopia;
back optic zone diameter;
meta-analysis
- From:
Recent Advances in Ophthalmology
2024;44(4):311-316
- CountryChina
- Language:Chinese
-
Abstract:
Objective To systematically evaluate the changes in axial length and treatment zone diameter among my-opic patients wearing orthokeratology lenses with different back optic zone diameters.Methods A comprehensive litera-ture search was conducted on PubMed,Embase,the Cochrane Library,Web of Science,Wangfang Med Online and CNKI databases in both Chinese and English to identify randomized controlled trials or controlled trials investigating orthokeratol-ogy lenses with varying back optical zone diameters.The literature was thoroughly reviewed by two researchers,who ex-tracted relevant data and conducted a methodological quality evaluation.Finally,meta-analysis was performed using Rev-Man 5.3 software.In all the included studies,orthokeratology lenses with a conventional back optic zone diameter were taken as the control group,while orthokeratology lenses with a reduced back optic zone diameter were utilized as the ex-perimental group.Results Eight studies involving 437 patients(459 eyes)with myopia were included.The results of me-ta-analysis showed that the axial length changes in the experimental group were significantly lower than those of the control group after wearing orthokeratology lenses for 6 months and 12 months(6 months:MD=-0.09,95％CI:-0.10 to-0.07,Z=10.50,P＜0.05;12 months:MD=-0.11,95％CI:-0.13 to-0.09,Z=12.19,P＜0.05);significant differ-ences in treatment zone diameter were observed between the experimental and control groups at various time points follow-ing orthokeratology lens wearing(MD=-0.82,95％CI:-1.04 to-0.59,Z=7.03,P＜0.05).Conclusion Orthoker-atology lenses designed with smaller back optical zone diameters can effectively delay axial length growth in myopic pa-tients,but their long-term efficacy needs to be confirmed.
