Research progress on the role of cardiac myosin binding protein-C in cardiovascular diseases
10.7683/xxyxyxb.2024.03.016
- VernacularTitle:心肌肌球蛋白结合蛋白-C在心血管疾病中的作用研究进展
- Author:
Binchao QIAO
1
;
Yongping JIA
;
Xiaoping CHEN
Author Information
1. 山西医科大学第一临床医学院,山西 太原 030001
- Keywords:
cardiac myosin binding protein-C;
cardiovascular disease;
mechanism of action
- From:
Journal of Xinxiang Medical College
2024;41(3):286-290,297
- CountryChina
- Language:Chinese
-
Abstract:
Cardiac myosin binding protein-C(cMyBP-C),as an important component of myocardium coarse filaments,can regulate cross-bridge circulation through phosphorylation or dephosphorylation and participates in myocardial systolic and diastolic functions.cMyBP-C plays an important role in the occurrence and development of cardiovascular diseases(CVDs)such as acute myocardial infarction,cardiomyopathy,heart failure,aortic stenosis,hypertensive myocardial hypertrophy,and myocarditis,but the specific mechanism has not been fully clarified.This article reviews the research progress on the role of cMyBP-C in CVDs,in order to provide references for the diagnosis,treatment and prognosis evaluation of CVDs.
