Correlation between HDL-C and red cell distribution width in patients with coronary heart disease
10.3969/j.issn.1008-0074.2023.06.07
- VernacularTitle:冠心病患者HDL-C与红细胞分布宽度的相关性
- Author:
Jin CHANG
1
;
Li-Jun LIU
;
Chun-De ZHANG
;
Shou-Kai LI
;
Bao-Ju YAO
Author Information
1. 安徽理工大学第一附属医院 (淮南市第一人民医院)心血管内科,安徽 淮南 232007
- Keywords:
Coronary disease;
Coronary stenosis;
Cholesterol,HDL
- From:
Chinese Journal of cardiovascular Rehabilitation Medicine
2023;32(6):580-584
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study correlation between high density lipoprotein-cholesterol(HDL-C)and red cell dis-tribution width(RDW)in patients with coronary heart disease(CHD).Methods:According to coronary stenotic severity,a total of 151 patients undergoing coronary CT angiography in our hospital were divided into CHD group(n=72)and non-CHD group(n=79).General clinical data were compared between two groups.Correlation be-tween HDL-C and RDW,influencing factors of CHD and diagnostic value of HDL-C and RDW for CHD were analyzed.Results:Compared with non-CHD group,there were significant rise in percentage of diabetes mellitus,age,serum triglyceride(TG)level and RDW,and significant reduction in serum HDL-C level in CHD group(P＜0.05 or＜0.01).Pearson correlation analysis indicated that serum HDL-C level was significant inversely correla-ted with RDW(r=-0.373,P=0.001),and there was a significant negative correlation between two indexes in CHD group and non-CHD group(r=-0.415,-0.243,P=0.001,0.031).Multivariate Logistic regression a-nalysis indicated that TG and RDW were independent risk factors for CHD(OR= 1.794,1.588,P=0.030,0.020),and HDL-C was its independent protective factor(OR=0.212,P=0.036).ROC curve indicated that AUC of combined detection of HDL-C and RDW diagnosing CHD was 0.674,its sensitivity was 58.33%and spe-cificity was 70.89%.Conclusion:RDW possesses certain diagnostic value for patients with coronary heart disease.
