Acute Cerebral Infarction, Deep Vein Thrombosis and Pulmonary Embolism in Kimura's Disease.
- Author:
Hyun Gu KANG
1
;
Soo Sung KIM
;
Jae Hoon JO
;
Hyung Jong PARK
;
Jin Sung CHEONG
;
Yeon Soo HA
;
Hak Seung LEE
;
Hyun Young PARK
;
Hyuk CHANG
;
Kwang Ho CHO
Author Information
1. Department of Neurology, Wonkwang University School of Medicine, Institute of Wonkwang Medical Science, Jeonbuk Regional Cardiocerebrovascular Disease Center, Iksan, Korea. seoulolympic@daum.net
- Publication Type:Case Report
- Keywords:
Kimura's disease;
Acute cerebral infarction;
Deep vein thrombosis;
Pulmonary embolism
- MeSH:
Angiography;
Biopsy;
Cerebral Infarction;
Dysarthria;
Eosinophilia;
Eosinophils;
Femoral Vein;
Fibrosis;
Head;
Humans;
Lower Extremity;
Middle Aged;
Neck;
Paresis;
Paresthesia;
Physical Examination;
Proteins;
Pulmonary Embolism;
Venous Thrombosis
- From:Korean Journal of Stroke
2011;13(2):85-88
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Kimura's disease is a chronic inflammatory disease producing subcutaneous tumor-like nodules chiefly in the head and neck region. It is characterized histologically by lymphoid follicles, intense aggregations of eosinophils, vascular proliferation and fibrosis combined with peripheral blood eosinophilia. We report a 56-year-old man who presented with dysarthria and right hemiparesis. On physical examination, a non-ender mass 5 x 6 cm was identified in the right submandibular area. He was diagnosed with Kimura's disease by biopsy. One month after admission, he complained of paresthesia in the left lower extremity. CT angiography revealed thromobosis in the left femoral vein and bilateral pulmonary embolism. To our knowledge, the concomitant occurrence of acute cerebral infarction, deep vein thrombosis and pulmonary embolism in patients with Kimura's disease has never been reported. Eosinophil-derived cytotoxic proteins are presumed to be fundamental to the pathogenesis of these disorders in Kimura's disease.
