Research advances in animal models of tricuspid regurgitation
10.3969/j.issn.1672-8467.2024.02.017
- VernacularTitle:三尖瓣反流动物模型研究进展
- Author:
Da-Wei LIN
1
;
Xiao-Chun ZHANG
;
Feng ZHANG
;
Wen-Zhi PAN
;
Da-Xin ZHOU
Author Information
1. 复旦大学附属中山医院心内科 上海 200032;上海市心血管病研究所 上海 200032
- Keywords:
tricuspid valve;
tricuspid regurgitation(TR);
animal model
- From:
Fudan University Journal of Medical Sciences
2024;51(2):257-261
- CountryChina
- Language:Chinese
-
Abstract:
Tricuspid regurgitation(TR)cases are widely distributed in China.Poor clinical drug efficacy,high surgical risk,and poor prognosis for right heart failure are found in patients with moderate or severe TR.In recent years,with the innovation of valve instruments and the development of technology,transcatheter tricuspid valve treatment could be a new choice for high-risk TR patients in surgery.Many TR animal models have emerged these years for the research of the mechanism of TR and for the clinical verification of instruments.Therefore,this review focuses on how to develop an animal model of TR and discusses the advantages and disadvantages of these techniques.