Function and research progress of ubiquitin-specific protease 7 in colorectal cancer

VernacularTitle:泛素特异性蛋白酶7功能和在结直肠癌中的研究进展
Author: Jincheng FU ¹ ; Tao FU
Author Information

1. 430060 武汉大学人民医院胃肠外Ⅱ科
Keywords: ubiquitin-specific protease 7; deubiquitination; colorectal cancer
From: Journal of Clinical Surgery 2024;32(1):106-109
CountryChina
Language:Chinese
Abstract: Ubiquitin-specific protease 7(USP7)is a deubiquitinating enzyme involved in a wide range of cellular processes,playing a key role in the regulation of cell proliferation and apoptosis,cell division,differentiation,DNA damage repair,epigenetic regulation and other biological processes.This article briefly summarizes the structure and extensive biological functions of USP7,and also describes the research progress of USP7 in colorectal cancer in recent years and potential directions for future research.