Research progress of no-reflow phenomenon after revascularization in acute ischemic stroke

VernacularTitle:急性缺血性脑卒中血管再通后无复流现象的研究进展
Author: Lei YUAN ¹ ; Xiao ZHANG ; Jianing WU
Author Information

1. 710068 西安医学院研究生处
Keywords: acute ischemic stroke; vascular recanalization; no-reflow phenomenon; treatment strategy
From: Journal of Clinical Neurology 2023;36(6):466-470
CountryChina
Language:Chinese
Abstract: Intravenous thrombolysis and revascularization in the time window are effective in promoting blood flow recanalization,reducing core infarction area and improving clinical prognosis in acute ischemic stroke(AIS).However,successful vascular recanalization does not mean the complete recovery of cerebral microcirculation perfusion,and the microstructure damage during ischemia may lead to microcirculation"no-reflow phenomenon(NRP)".In recent years,studies have found that about 40%of patients with AIS can have NRP after vascular recanalization,which is one of the important reasons for futile recanalization after vascular therapy in AIS.Therefore,early identification and treatment of NRP after recanalization treatment of AIS is of great significance to improve the prognosis.This article reviews the related definition,pathophysiological mechanism,imaging features and treatment strategies of NRP after vascular recanalization in AIS,in order to provide a reference for clinical diagnosis and treatment after vascular recanalization in AIS.