Clinical study on the occurrence of multiple organ dysfunction syndrome in patients with basal ganglia hypertensive intracerebral hemorrhage and its influencing factors
10.3969/j.issn.1004-1648.2023.06.003
- VernacularTitle:基底节高血压性脑出血患者多器官功能障碍综合征发生情况及其影响因素的临床研究
- Author:
Xiaohong XUE
1
;
Shuangyuan MA
;
Jinhua CAO
Author Information
1. 314000 嘉兴,武警海警总队医院神经外科
- Keywords:
cerebral hemorrhage;
influencing factors;
multiple organ dysfunction syndrome;
predictive value
- From:
Journal of Clinical Neurology
2023;36(6):410-414
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the occurrence of multiple organ dysfunction syndrome(MODS)in patients with basal ganglia hypertensive intracerebral hemorrhage,and analyze its influencing factors.Methods A total of 100 patients with cerebral hemorrhage in our hospital were selected as the research objects.Patients were divided into MODS group and non-MODS group according to whether or not the occurrence of MODS occurred.The clinical data of the two groups were collected.Logistic regression was used to analyze related influencing factors,and ROC curve was used to evaluate the predictive value of Logistic regression model.Results The Logistic regression equation showed that age,time from onset to admission,hematoma volume,Acute Physiology and Chronic Health Status Rating System Ⅱ(APACHEⅡ)score,duration of postoperative mechanical ventilation,fasting plasma glucose(FPG)and delayed surgery were all independent risk factors for the occurrence of MODS in patients with basal ganglia hypertensive cerebral haemorrhage,and GCS score was an independent protective factor for the occurrence of MODS in patients with basal ganglia hypertensive cerebral haemorrhage(all P＜0.05).The ROC curve plotted according to predicted and true values showed that when Log(P)＞3.74,the sensitivity was 84.62%and the specificity was 90.16%;the standard regression coefficients calculated by the partial standardization method yielded that in the Logistic regression analysis.The independent influencing factors in order of importance were APACHEⅡ score,age,FPG,haematoma volume,postoperative mechanical ventilation time,GCS score,time from onset to admission,and delayed surgery.Conclusions Affected by many factors such as age,time from onset to hospital admission,hematoma volume,APACHEⅡ score,postoperative mechanical ventilation time,FPG and so on,patients with cerebral hemorrhage are at risk of MODS.In clinical work,the management of the above factors can be strengthened to reduce the incidence of MODS.
