Risk factors for newly developed lower extremity deep vein thrombosis in patients after general anes-thesia in the anesthesia intensive care unit
- VernacularTitle:全麻患者术后麻醉重症监护室中新发下肢深静脉血栓的危险因素
- Author:
Xiaofei WANG
1
;
Mingyang SUN
;
Jiaqiang ZHANG
Author Information
- Keywords: Lower extremity deep vein thrombosis; General anesthesia; Anesthesia intensive care unit; Risk factors
- From: The Journal of Clinical Anesthesiology 2024;40(1):56-60
- CountryChina
- Language:Chinese
- Abstract: Objective To identify the risk factors for newly developed lower extremity deep vein thrombosis(DVT)in patients transferred to the anesthesia intensive care unit(AICU)after general anes-thesia.Methods A total of 192 patients who were transferred to AICU with tracheal intubation after elective general anesthesia from May 2022 to August 2022,105 males and 87 females,aged 18-85 years,BMI 18-31 kg/m2,ASA physical status Ⅱor Ⅲ,were retrospectively collected.The patients'baseline da-ta,anesthesia surgery data and preoperative and postoperative laboratory examination data were obtained.The patients were divided into two groups according to the results of ultrasound within 6 hours after admission to the AICU:DVT group and non-DVT group.Multivariate logistic regression analysis was used to analyze the risk factors and 95%confidence interval(CI)of DVT in AICU patients within 6 hours after sur-gery.ResultsNew DVT occurred in 64 patients(33.3%)in AICU after general anesthesia were calf inter-muscular venous thrombosis(CMVT).Multivariate logistic regression analysis showed that preoperative ar-rhythmia(OR = 2.236,95%CI 1.011-4.943,P = 0.047),high preoperative platelet count(OR = 1.006,95%CI 1.002-1.010,P = 0.007),high preoperative D-dimer concentration(OR=1.203,95%CI 1.046-1.383,P = 0.010),intraoperative hypotension(OR = 1.010,95%CI 1.002-1.019,P = 0.020),and intraoperative norepinephrine application(OR = 3.796,95%CI 1.697-8.492,P = 0.001)were risk factors for new DVT formation in AICU patients after general anesthesia.History of regular intake of aspirin(OR = 0.176,95%CI 0.060-0.518,P = 0.002)was protective factor.Conclusion Preoperative arrhythmia,high preoperative platelet count,high preoperative D-dimer concentration,intraop-erative hypotension,and administration of intraoperative norepinephrine are risk factors for new DVT within 6 hours after general anesthesia in AICU patients.
