Research progress on the role of the TMEM family of transmembrane proteins in the human reproductive system
10.16352/j.issn.1001-6325.2024.04.0568
- VernacularTitle:跨膜蛋白TMEM家族在人类生殖系统中作用的研究进展
- Author:
Liu YANG
1
;
Hui TIAN
;
Yuanyuan JI
;
Xiaofang HAN
Author Information
1. 山西医科大学附属第五临床医学院 (山西省人民医院) 中心实验室,太原 030012
- Keywords:
transmembrane protein;
infertility;
reproductive health
- From:
Basic & Clinical Medicine
2024;44(4):568-571
- CountryChina
- Language:Chinese
-
Abstract:
The transmembrane protein(TMEM)family exhibits widespread distribution across both the plasma membrane and organelle membranes,actively participating in the intricate regulation of diverse pathophysiological processes.Contemporary investigations have uncovered the pivotal involvement of the TMEM family in the human reproductive system.This family is found to play a crucial role in regulating spermatogenesis,sperm-egg fusion,en-dometrial receptivity,as well as tumor invasion and migration.These findings highlight its intricate association with the onset and progression of various diseases.A comprehensive identification of the function of TMEM family in hu-man reproductive system holds significant importance,offering profound insights into the nuanced biological func-tions of this protein family.This in-depth examination not only supports our understanding about the complex mech-anisms controlling reproductive processes but also lay a foundation for potential advancements in medical research.
