Zinc deficiency during pregnancy and its effect on pregnancy outcome
10.16352/j.issn.1001-6325.2024.04.0422
- VernacularTitle:孕期锌缺乏及对妊娠结局的影响
- Author:
Yunlong LI
1
;
Rui LI
;
Yuping ZHANG
;
Rui WANG
;
Yanping LIU
Author Information
1. 中国医学科学院 北京协和医学院 北京协和医院 临床营养科,北京 100730
- Keywords:
zinc deficiency;
zinc biomarkers;
pregnancy outcome
- From:
Basic & Clinical Medicine
2024;44(4):422-427
- CountryChina
- Language:Chinese
-
Abstract:
Zinc deficiency during pregnancy is common and has been significantly associated with adverse pregnancy outcomes such as spontaneous preterm birth(PTB),recurrent abortion(RA),low birth weight(LBW),small-for-gestational-age infant(SGA),preeclampsia(PE),and gestational diabetes mellitus(GDM).Unfortunately,there is no specific biomarkers which are sensitive,easy-to-collect and detect available for the clini-cal evaluation of zinc nutritional status.However,recent studies have identified metallothionein and the ratio of oleic acid to dihydroxymethyl gamma-linolenic acid(LA/DGLA)as potentially candidates of biomarkers.This article focuses on summarizing and discussing the progress of domestic and international researches on zinc deficiency dur-ing pregnancy and adverse pregnancy outcomes,potential zinc biomarkers,and zinc deficiency treatments,aiming at providing ideas for perinatal nutritional guidance.
