Research progress in neutrophil-mediated delivery systems
10.3760/cma.j.cn121382-20231107-00107
- VernacularTitle:基于细胞外囊泡的递送系统研究进展
- Author:
Limin JIN
1
;
Feng LYU
;
Xia DONG
Author Information
1. 中国医学科学院 北京协和医学院生物医学工程研究所，天津 300192
- Keywords:
Extracellular vesicles;
Intercellular communication;
Targeted delivery
- From:
International Journal of Biomedical Engineering
2024;47(1):39-44
- CountryChina
- Language:Chinese
-
Abstract:
Extracellular vesicles are recognized as a kind of membranous vesicle derived from endosomes and cell membranes that play important roles in intercellular communication. Strict biogenesis pathways dictate that extracellular vesicles have a wide range of origins and specific parental characteristics, while complex contents and surface proteins facilitate their recognition by receptor cells. Extracellular vesicles are considered a promising drug delivery system due to their natural biocompatibility and vesicle structure, where more functional biomolecules can be accommodated. The classification, biological functions, and characteristics of extracellular vesicles in different types of drug delivery were introduced. The application of extracellular vesicles in disease therapy and the clinical transformation and challenges of the extracellular vesicle delivery system were discussed.
