Advances in the pathogenesis of postural tachycardia syndrome in children
10.3760/cma.j.issn.1673-4408.2024.02.008
- VernacularTitle:儿童体位性心动过速综合征的发病机制研究进展
- Author:
Yao XIAO
1
;
Yuanxiang OU
Author Information
1. 长沙市第三医院儿科 410000
- Keywords:
Children;
Postural tachycardia syndrome;
Pathogenesis
- From:
International Journal of Pediatrics
2024;51(2):103-106
- CountryChina
- Language:Chinese
-
Abstract:
Hypovolemic and hemodynamic disorders,autonomic nervous dysfunction and hyperadrenergic state are recognized pathogenesis of postural tachycardia syndrome(POTS). According to this,POTS can be divided into three types:hypovolemic POTS,neurogenic POTS and hyperadrenergic POTS. Autoimmune abnormalities,changes in hormone levels,and gene mutations may also cause POTS. In addition,some patients have joint overactivity syndrome,functional gastrointestinal disorders,Ehlers Danlos syndrome,mast cell activation disorders and other diseases.Therefore,POTS is a complex clinical syndrome that may involve multiple mechanisms.This article aims to offer clinicians an improved understanding of the pathogenesis of pediatric POTS through a comprehensive review of this disease.