Progress on risk factors involved in airway mucus hypersecretion in children with community acquired pneumonia
10.3760/cma.j.issn.1673-4408.2024.01.008
- VernacularTitle:社区获得性肺炎儿童发生气道黏液高分泌的危险因素研究进展
- Author:
Chunyu YAN
1
;
Yu DENG
Author Information
1. 重庆医科大学附属儿童医院呼吸科 国家儿童健康与疾病临床医学研究中心 儿童发育疾病研究教育部重点实验室 儿童感染与免疫罕见病重庆市重点实验室 400014
- Keywords:
Community acquired pneumonia;
Airway mucus hypersecretion;
Plastic bronchitis;
Risk factors
- From:
International Journal of Pediatrics
2024;51(1):38-42
- CountryChina
- Language:Chinese
-
Abstract:
Airway mucus hypersecretion is one of the pathological changes in children with community acquired pneumonia（CAP），and affects the severity，progression and prognosis of CAP.Diagnosis of airway mucus hypersecretion currently relies on fiberoptic bronchoscopy. To predict the risk of airway mucus hypersecretion and to take early action to avoid serious consequences such as plastic bronchitis and hypoxia and respiratory failure，the article summarizes the relationship between age，clinical characteristics and laboratory indices and the formation of airway mucus hypersecretion in children with CAP. Among them，age，pathogenic species，fever peak and fever range，neutrophil ratio，C-reactive protein，lactate dehydrogenase，D-dimer，serum 25（OH）D，and some interleukins，interferons，and acquired immune indicators have an early warning effect on the development of airway mucus hypersecretion in children with CAP.
