Regulatory role of eosinophils in respiratory infectious diseases
10.3760/cma.j.issn.1673-4408.2024.01.003
- VernacularTitle:嗜酸性粒细胞对呼吸道感染性疾病的调节作用
- Author:
Chaofen WU
1
;
Lina CHEN
Author Information
1. 四川大学华西第二医院小儿呼吸免疫科 出生缺陷与相关妇儿疾病教育部重点实验室 国家卫生健康委员会时间生物学重点实验室(四川大学)，成都 610041
- Keywords:
Eosinophil;
Respiratory tract infection;
Regulating effect
- From:
International Journal of Pediatrics
2024;51(1):12-16
- CountryChina
- Language:Chinese
-
Abstract:
Eosinophils are generally considered to play an important role in parasitic infections and allergic diseases. In recent years，eosinophils have also been found to be involved in the host's immune response to infections caused by bacteria，viruses and fungi. Eosinophils recognize these pathogens through pattern recognition receptors，during this process multiple mechanisms are implicated in host's immune defense against infections. Much progress on the role of eosinophils in respiratory tract infections has been reported in recent years. This review summarizes the regulatory role of eosinophils in respiratory infectious diseases，and the activation process of eosinophils and their direct and indirect interaction with respiratory pathogens，hoping to improve the recognition of the role of eosinophils in the pathogenesis of respiratory infectious diseases，and provide new ideas for clinical diagnosis and treatment.
