Research progress on anatomic vascular reconstruction in rat models of orthotopic liver transplantation
10.3969/j.issn.1674-7445.2024037
- VernacularTitle:大鼠原位肝移植解剖重建研究进展
- Author:
Weikang WU
1
;
Xiao LI
1
;
Xudan WANG
1
;
Rui DING
1
;
Kaishan TAO
1
Author Information
1. Department of Hepatobiliary-pancreatic-splenic Surgery, Xijing Hospital of Air Force Medical University, Xi’an 710032, China.
- Publication Type:ReviewArticle
- Keywords:
Orthotopic liver transplantation;
Rat;
Vascular anastomosis;
Magnetic ring anastomosis;
Suprahepatic inferior vena cava;
Portal vein;
Infrahepatic inferior vena cava;
Bile duct
- From:
Organ Transplantation
2024;15(3):469-473
- CountryChina
- Language:Chinese
-
Abstract:
Establishment of rat models of liver transplantation provides an ideal animal model for resolving the problems of postoperative complications and perioperative treatment of liver transplantation. With in-depth study of the establishment of rat models of liver transplantation, classic "two-cuff" technique has been gradually employed. However, poor surgical field, vascular torsion, biliary tract injury and long anhepatic phase remain unresolved in the process of liver transplantation using traditional techniques. At present, the rat models of liver transplantation at home and abroad are modified mainly from the reconstruction of four vital anatomic structures including the suprahepatic inferior vena cava, portal vein, infrahepatic inferior vena cava and bile duct. Therefore, the latest progress in the reconstruction of the suprahepatic inferior vena cava, portal vein, infrahepatic inferior vena cava and bile duct was reviewed, aiming to provide reference for the establishment of rat models of liver transplantation and promote further development of liver transplantation techniques.
