Two new dalbergiphenols from Zhuang medicine Dalbergia rimosa Roxb
10.16438/j.0513-4870.2023-0782
- VernacularTitle:壮药多裂黄檀中2个新的黄檀酚类化合物
- Author:
Cheng-sheng LU
1
;
Wei-yu WANG
2
;
Min ZHU
2
;
Si-si QIN
2
;
Zhao-hui LI
2
;
Chen-yan LIANG
2
;
Xu FENG
2
;
Jian-hua WEI
2
Author Information
1. Teaching Center of Experiment and Practical Training, Guangxi University of Chinese Medicine, Nanning 530200, China; Ruikang Hospital Affiliated to Guangxi University of Chinese Medicine, Nanning 530011, China; National Demonstration Center for Experimental Chinese Medicine Education, Guangxi University of Chinese Medicine, Nanning 530200, China
2. Teaching Center of Experiment and Practical Training, Guangxi University of Chinese Medicine, Nanning 530200, China; College of Pharmacy, Guangxi University of Chinese Medicine, Nanning 530200, China; National Demonstration Center for Experimental Chinese Medicine Education, Guangxi University of Chinese Medicine, Nanning 530200, China
- Publication Type:Research Article
- Keywords:
italic>Dalbergia rimosa Roxb.;
chemical composition;
albergiphenol;
antioxidant
- From:
Acta Pharmaceutica Sinica
2024;59(2):418-423
- CountryChina
- Language:Chinese
-
Abstract:
Twelve compounds were isolated from the ethyl acetate fraction of the 80% aqueous ethanol extract of the roots and stems of Dalbergia rimosa Roxb. by silica gel, MCI, Sephadex LH-20 column chromatography, and semi-preparative HPLC. Their structures were identified by spectral analysis such as UV, IR, MS, 1D/2D NMR and by comparison with literature information as dalbergiquinol A (1), dalbergiquinol B (2), R-(-)-3′-hydroxy-2,4,5-trimethoxydalbergiquinol (3), neokhriol A (4), mucronulatol (5), (3R)-7,2′,3′-trihydroxy-4′-methoxy-isoflavane (6), isomucronulatol (7), (3S)-violanone (8), 3′-O-methylviolanone (9), eryvarin M (10), (±)-α,3,4,2′,4′-pentahydroxydihydrochalcone (11) and (-)-butin (12). Compound 1 and 2 are new compounds, and compounds 3-12 were isolated from this plant for the first time. Compounds 1, 2, 4, 6, 8, 11, 12 showed good scavenging effect on DPPH free radical.
