Research progress on the mechanism of subthreshold micropulse laser photocoagulation in central serous chorioretinopathy
10.3980/j.issn.1672-5123.2024.5.16
- VernacularTitle:阈值下微脉冲激光在中心性浆液性脉络膜视网膜病变中的作用机制
- Author:
Xue LU
1
;
Bing XIE
1
Author Information
1. Department of Ophthalmology, Affiliated Hospital of Zunyi Medical University, Zunyi 563000, Guizhou Province, China
- Publication Type:Journal Article
- Keywords:
central serous chorioretinopathy;
subthreshold micropulse laser photocoagulation;
retinal pigment epithelium;
endothelial cells of the choroidal capillaries;
mechanism
- From:
International Eye Science
2024;24(5):749-752
- CountryChina
- Language:Chinese
-
Abstract:
Central serous chorioretinopathy(CSC)is a common macular degeneration that primarily affects young patients. While the disease may resolve on its own to some extent, delayed or inadequate treatment can result in recurrence and progression to chronic CSC. This can lead to complications such as retinal pigment epithelium(RPE)atrophy and choroidal neovascularization, ultimately causing irreversible damage to central vision. Subthreshold micropulse laser photocoagulation(SMLP)is a type of laser therapy that differs from traditional lasers in that it does not cause damage or thermal injury to RPE cells and photoreceptors. SMLP has become widely used in clinical treatment of CSC due to its effectiveness, safety, and reproducibility, particularly in cases where verteporfin is not available in photodynamic therapy(PDT). The purpose of this review is to explain the mechanism of SMLP in CSC and summarize the effector cells, cytokines, and mechanisms of action involved in its treatment. This will provide a theoretical basis for promoting and rationalizing the use of SMLP in clinical practice.
