Gastric Mucosa-associated Lymphoid Tissue Lymphoma Based on Outcome of Domestic Treatment.
10.4166/kjg.2016.68.4.175
- Author:
Jin Tae JUNG
1
Author Information
1. Department of Internal Medicine, Catholic University of Daegu School of Medicine, Daegu, Korea. jungjt@cu.ac.kr
- Publication Type:Review
- Keywords:
Mucosa-associated lymphoid tissue;
Stomach;
Therapy
- MeSH:
Chromosome Aberrations;
Drug Therapy;
Endoscopy;
Helicobacter pylori;
Humans;
Korea;
Lymphoid Tissue;
Lymphoma;
Lymphoma, B-Cell, Marginal Zone*;
Lymphoma, Non-Hodgkin;
Radiotherapy;
Recurrence;
Stomach;
Ulcer
- From:The Korean Journal of Gastroenterology
2016;68(4):175-178
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is associated with Helicobacter pylori infection. H. pylori eradication can be performed as a primary therapy regardless of H. pylori status. In Korea, six articles were published about low-grade gastric MALT lymphoma with H. pylori. Complete regression rate after H. pylori eradication is reported at 74.5% to 94.4%. Radiotherapy results in favorable clinical long-term outcomes in patients with early-stage gastric MALT lymphoma who fail H. pylori eradication therapy and those who are H. pylori negative. Chemotherapy could be reserved for patients with metastatic or high-grade lymphoma. In gastric MALT lymphoma, patients with polypoid type on initial endoscopy had a higher likelihood of recurrence than those with diffuse infiltration or ulceration types. The depth of invasion, location of lesions, and chromosomal abnormality with t(11;18) together are predictive factors for failure to remission by H. pylori eradication.
