Research progress on antipyretic effect of Chinese medicine
- Author:
Shengfu CHEN
1
;
Weigang WANG
1
;
Weize DU
1
;
Maoxing LI
1
;
Shengfu CHEN
2
;
Xiaolin LI
2
;
Weigang WANG
2
;
Weize DU
2
;
Maoxing LI
2
;
Shengfu CHEN
3
;
Xiaolin LI
3
;
Weigang WANG
3
;
Weize DU
3
;
Maoxing LI
3
;
Maoxing LI
4
Author Information
- Publication Type:Journal Article
- Keywords: Active ingredients of traditional Chinese medicine; Antipyretic; Fever; Nuclear transcription factor κB signaling pathway
- From: Chinese Journal of Clinical Pharmacology and Therapeutics 2022;27(3):334-344
- CountryChina
- Language:Chinese
- Abstract: Fever is a sign of infection and inflammatory diseases in the body. Persistent high fever will lead to cell degeneration, causing multiple organ dysfunction, and seriously affecting brain nerve and tissue function. Although the fever process is common and ordinary, its pathological mechanism involves multiple signaling pathways, such as nuclear transcription factor κB signaling pathway, Toll-like receptor 4 signaling pathway. A large number of studies have shown that traditional Chinese medicine compound and its active components can reduce serum inflammatory factors (TNF-α, IL-1β and IL-6) and hypothalamic thermoregulatory mediators (PGE
