Study on the effect of vitamin D on diabetic neuropathy through mitochondrial/autophagy pathway

Author: Jia BAI ¹ ; Hong YANG ¹ ; Lingling LI ¹ ; Yangyang ZHANG ¹ ; Ying YANG ¹ ; Jia BAI ² ; Hong YANG ² ; Lingling LI ² ; Yangyang ZHANG ² ; Ying YANG ² ; Haihong LJ ²
Author Information

1. The First Clinical Medical College, Lanzhou University
2. Department of Endocrinology, The First Hospital of Lanzhou University
Publication Type:Journal Article
Keywords: autophagy; diabetic neuropathy; mitochondrial; oxidative stress; vitamin D
From: Chinese Journal of Clinical Pharmacology and Therapeutics 2023;28(2):214-219
CountryChina
Language:Chinese
Abstract: The main function of vitamin D is to regulate calcium homeostasis and bone metabolism, but in recent years, it has also been confirmed that it can participate in mitochondrial metabolism and autophagy, and further affect skeletal muscle cells, liver cells, nerve cells, etc. This article mainly discusses the effect of vitamin D on diabetic neuropathy by improving mitochondrial function and regulating autophagy, so as to provide a theoretical basis for the clinical application of vitamin D.