Amelioration and protection of nervonic acid on motor disorder in mice with Parkinson's disease
10.3969/j.issn.1001-1978.2021.11.009
- Author:
Dan-Dong HU
1
;
Dan-Dong HU
2
;
Yu-Juan CUI
2
;
Ji ZHANG
2
;
Yu-Juan CUI
3
Author Information
1. Beijing Yanqing District Food and Drug Safety Monitoring Center
2. School of Life Science, Northwest Normal University
3. Beijing Yanqing Center for Disease Prevention and Control
- Publication Type:Journal Article
- Keywords:
a-synuclein;
DA;
DAT;
inflammation response;
motor disorder;
nervonic acid;
Parkinson's disease;
T H
- From:
Chinese Pharmacological Bulletin
2021;37(11):1524-1529
- CountryChina
- Language:Chinese
-
Abstract:
Aim To investigate the potential protective function of nervonic acid (NA) on the motor disorder in mice subjected to MPTP and the underlying mechanism. Methods The PD mice model was constructed and divided into control group, model group, nervonic acid (20 mg • k g