Effect of a novel phosphodiesterase type 5 inhibitor, CPD1, on carbon tetrachloride-induced liver fibrosis in mice
- Author:
Wen-Bin FENG
1
;
Jian-Qin YANG
1
;
Xin-Hui CHEN
1
;
Zhong-Lian XIE
1
;
Ying-Ying ZHANG
1
;
Ying-Xi CHEN
1
;
Zi-Jian ZHAO
1
;
Yun-Ping MU
1
;
Fang-Hong LI
1
Author Information
- Publication Type:Journal Article
- Keywords: activation; carbon tet-rachloride; CPD1; hepatic stellate cells; liver fibrosis; phosphodiesterase type 5 inhibitors
- From: Chinese Pharmacological Bulletin 2023;39(3):470-476
- CountryChina
- Language:Chinese
- Abstract: Aim To investigate the effects of CPD1, a novel phosphodiesterase 5 inhibitor, on liver pathological phenotype and hepatic stellate cells (HSCs) activation in hepatic fibrosis model mice caused by carbon tetrachloride ( CCl
