Research progress on regulatory mechanism of long non-coding RNA CYTOR in human cancer

Shao-Kang SUN; Lin YI; Yong HUANG; Xiao-Yan LIU; Yu ZHAO; Feng LONG; Feng LONG; Feng LONG

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Research progress on regulatory mechanism of long non-coding RNA CYTOR in human cancer

Author: Shao-Kang SUN ¹ ; Lin YI ¹ ; Yong HUANG ¹ ; Xiao-Yan LIU ¹ ; Yu ZHAO ¹ ; Feng LONG ¹ ; Feng LONG ² ; Feng LONG ³
Author Information

1. Basic Medical College, Gansu University of Chinese Medicine
2. Gansu Provincial Key Laboratory of Traditional Basic Medical College, Chinese Medicine for Prevention and Treatment of Chronic Diseases
3. Provincial-Level Key Laboratory for Molecular Medicine of Major Disease and Treatment with Traditional Chinese Medicine Research, Gansu Colleges and Universities
Publication Type:Journal Article
Keywords: cancer; cancer related signaling pathways; clinical features of cancer; CYTOR; LncRNA; regulators; regulatory mechanism
From: Chinese Pharmacological Bulletin 2023;39(3):419-424
CountryChina
Language:Chinese
Abstract: Cancer is difficult to cure because of its heterogeneity, drug resistance and easy recurrence and metastasis. Revealing the molecular mechanism of cancer genesis and development, identifying new diagnostic markers and molecular therapeutic targets are undoubtedly effective strategies to solve the problems of early diagnosis, treatment and improvement of prognosis of cancer patients. More and more studies have shown that long non-coding RNA (IncRNA) is specifically expressed in human cancer and is a key regulator of cancer occurrence and development. Cytoskeleton regulator RNA (CYTOR) is a carcinogenic lncRNA found in recent years. CYTOR is highly expressed in many types of cancer and regulates the development of cancer through a variety of pathways, which may be an effective biomarker for early cancer diagnosis, molecular targeted therapy and prognosis assessment. This paper reviews the molecular regulatory mechanism and related biological characteristics of CYTOR in human cancer, in order to provide new scientific reference for clinical cancer diagnosis and treatment.