Mechanism of quercetin regulating p38 MAPK/NF-kB/NLRP3 signaling pathway in rats with secretory otitis media

Author: Yue-Tian WANG ¹ ; Xin-Guo LIU ¹ ; Yong YANG ²
Author Information

1. Dept of Otolaryngology, Zhumadian Central Hospital Directly Affiliated to Huanghuai College
2. Dept of Pharmacology, School of Pharmacy, Jinzhou Medical University
Publication Type:Journal Article
Keywords: inflammatory response; NOD-like receptor protein 3; nuclear transcription factor-KB; p38 mi-togen-activated protein kinase; quercetin; secretory otitis media
From: Chinese Pharmacological Bulletin 2023;39(4):672-678
CountryChina
Language:Chinese
Abstract: Aim To investigate the effect of quercetin (Que) on secretory otitis media (SOM) rats and its mechanism. Methods Forty-eight male SD rats were selected and randomly divided into control group (control), model group (model), Que group (100 mg • kg